Steroid Side Effect

INTRODUCTION

I. BACKGROUND

From there, the anti-inflammatory drugs containing steroids have contributed to reverse many diseases due to the inhibitory effect against the inflammatory response such as status congestion, edema of the organization which is known as reactive inflammation.

As the drugs take effect on most types of inflammation regardless of the cause. The reaction of anti-inflammatory drugs of this type is represented by the mechanism: Inhibition of prostaglandin biosynthesis by preventing the formation of cyclo-oxygenase is an enzyme that promotes the effects of the prostaglandins (a hormone related to the regulate some body functions such as inflammation, body temperature, muscle). It is known that no cyclo-oxygenase can not make prostaglandins, which in the absence of prostaglandin is no inflammation, pain, fever. On the other hand drugs can also sustainable primary lybosom cell membrane to instant resolution and suppression of inflammation, and resistance to the chemical mediator of inflammation. In addition, it also works to reduce fever, relieve pain and anti-platelet agglutination.

With the important role of the anti-inflammatory drugs do not contain steroids, people have said its application to the field to manufacture drugs for his life.

Medicines are special goods product, a direct relationship to public health, the quality and effectiveness of the prevention and treatment and the relationship to the life of the patient ... So, DRUGS must been seriously tested from raw material to finished product to see lots of medicines concluded that passing or failing the quality standards to determine which drugs have been lot circulation is put to use to for treatment goals or not.

Based on this theme: "TESTING SOME NON-steroid anti-inflammatory drugs" is done.

II. OBJECTIVES OF RESEARCH TOPICS

Conducted to quantify the active ingredient of some anti-inflammatory drugs do not contain steroids.

Assessment of quality criteria for each batch of products based on specified criteria, and on that basis concluded that there are lots of medicines see circulated on the market, is used to serve the objectives of treatment or not.

Assess the reliability of the method through the determination of the linearity of standard quality, the correct strength, precision, specificity of the product.

Calculate the number of samples to be analyzed to a minimum cost.

OVERVIEW

ABOUT I.TONG steroids

I.1 Introduction to steroid

Steroids are a group of hydrocarbons with four rings are made of cholesterol and related substances. Many of the important hormone of the body (eg, estrogen